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Health-Related Quality of Life among Patients with Celiac Disease in Saudi Arabia Introduction celiac disease

Health-Related Quality of Life among Patients with Celiac Disease in
Saudi Arabia

Introduction
celiac disease (CD) can have a large negative impact on the quality of patients’ life. Celiac disease is a genetical autoimmune disorder characterized by hypersensitivity to gluten which is a main protein found in different type of food including wheat and grains.
Aims: to estimate the health-related quality of life in patients with celiac disease.

Methods:
Cross sectional study using self-administrated Short-Form survey (SF-36) questionnaire that has been done by CD patients in kingdom Saudi Arabia.Researchers conducted the study by using self-administrated Short- Form survey (SF-36) questionnaire that has been done by patients or their parents. Study subjects was are All patients who are diagnosed with celiac disease satisfying the criteria.The SF – 36 questionnaires have been sent to one of the famous celiac group advocacy social group.

Results:
A total of 264 subjects, 72.7% of them were females while 27.3% were males. 23.9% were between 5 – 14 years, 26.1% were between 15-24 years, 48.9% were between 25–64 and 1.1% = 64 years. SF-36 has 8 subscales: physical functioning, Role limitations due to physical health, Role limitations due to emotional problems, energy/fatigue, emotional wellbeing, social functioning, pain, and general health Table 1. Emotional well-being had the lowest mean (mean=57.8, 20.3 SD) compared to baseline (mean=70.38, 21.9 SD) then social functioning mean=67.95 (baseline=78.77), 23.16 SD (baseline=25.4SD) followed by Role functioning/emotional mean=55.8 (baseline=65.78), 43 SD (baseline=40.7SD). However, females scored significantly lower than males in Role functioning/physical (females: 51.56, males: 70.14) and Role functioning/emotional (females: 50.52, males: 69.91) Table 2. Patient’s = 64 years scored lowest in Role functioning/ emotional (33.33, 57.74SD). Patients who are adherent to GFD scored higher than non-adherent patients. Especially in role functioning/physical (59.13-44.64) and role functioning/ emotional (58.3-45.24).

Conclusion:
HRQOL in celiac patients scored low in all subscales. However, Emotional well-being, social functioning and Role functioning/emotional were the most significant. Females scored lower than males in all subscales except in general health. Furthermore, Adherence to GFD has a major role in improving HRQOL.